Stephen H Leppla Selected Research

Capsules (Microcapsules)

1/2015	Anthrax Pathogenesis.
1/2011	Pre- and postexposure protection against virulent anthrax infection in mice by humanized monoclonal antibodies to Bacillus anthracis capsule.

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Stephen H Leppla Research Topics

Disease

106	Anthrax 01/2023 - 02/2002
39	Neoplasms (Cancer) 01/2023 - 02/2002
22	Infections 01/2021 - 06/2002
21	Edema (Dropsy) 01/2022 - 11/2005
10	Melanoma (Melanoma, Malignant) 07/2022 - 01/2003
6	Shock 12/2015 - 02/2004
5	Inflammation (Inflammations) 01/2020 - 03/2006
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2015 - 10/2004
3	Peritonitis 01/2016 - 01/2014
2	Hypoxia (Hypoxemia) 01/2021 - 09/2003
2	Toxemia 05/2019 - 01/2004
2	Gout 01/2016 - 03/2015
2	Hypotension (Low Blood Pressure) 01/2009 - 05/2007
2	Sepsis (Septicemia) 06/2007 - 02/2005
1	Ovarian Neoplasms (Ovarian Cancer) 12/2022
1	Pain (Aches) 01/2022
1	Parkinson Disease (Parkinson's Disease) 05/2019
1	Inhalation anthrax 05/2019
1	Plague (Bubonic Plague) 10/2018
1	Astrocytoma (Pilocytic Astrocytoma) 05/2016
1	Bacterial Infections (Bacterial Infection) 06/2014
1	Toxoplasmosis 02/2014

Drug/Important Bio-Agent (IBA)

40	anthrax toxin (anthrax lethal factor)IBA 01/2023 - 02/2002
35	AntigensIBA 01/2022 - 01/2003
34	Proteins (Proteins, Gene)FDA Link 01/2023 - 02/2002
18	InflammasomesIBA 12/2020 - 02/2008
16	Virulence Factors (Pathogenicity Factors)IBA 01/2020 - 07/2003
14	Peptide Hydrolases (Proteases)FDA Link 12/2022 - 02/2002
14	edema factorIBA 01/2022 - 06/2008
12	Matrix Metalloproteinases (MMPs)IBA 07/2022 - 06/2005
11	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 07/2022 - 01/2003
10	anthrax toxin receptorsIBA 07/2022 - 09/2005
10	VaccinesIBA 10/2018 - 07/2002
10	Mitogen-Activated Protein KinasesIBA 10/2015 - 01/2003
8	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2023 - 01/2003
8	Plasminogen Activators (Plasminogen Activator)IBA 07/2022 - 01/2003
8	ExotoxinsIBA 06/2014 - 02/2002
7	Monoclonal AntibodiesIBA 09/2013 - 02/2005
6	FurinIBA 10/2019 - 01/2004
6	AntibodiesIBA 08/2015 - 08/2002
5	Adenylyl Cyclases (Adenylyl Cyclase)IBA 01/2021 - 11/2005
5	Anti-Bacterial Agents (Antibiotics)IBA 10/2016 - 10/2005
5	Diphtheria ToxinIBA 07/2009 - 02/2002
4	Neutralizing AntibodiesIBA 01/2022 - 06/2002
4	Phosphotransferases (Kinase)IBA 12/2020 - 07/2003
4	Peptides (Polypeptides)IBA 01/2015 - 02/2002
4	GelatinasesIBA 01/2010 - 03/2008
4	CytokinesIBA 06/2008 - 02/2004
3	ProdrugsIBA 12/2022 - 01/2006
3	Bacterial ToxinsIBA 01/2022 - 05/2003
3	EnzymesIBA 04/2013 - 02/2002
3	LigandsIBA 11/2004 - 08/2002
2	Serine Proteases (Serine Protease)IBA 12/2022 - 10/2015
2	adefovirIBA 01/2021 - 03/2011
2	AntitoxinsIBA 01/2021 - 01/2011
2	Metalloproteases (Metalloproteinases)IBA 05/2019 - 09/2008
2	Plague VaccineIBA 10/2018 - 01/2017
2	Single-Domain AntibodiesIBA 10/2016 - 03/2015
2	NucleotidesIBA 01/2016 - 02/2014
2	Uric Acid (Urate)IBA 03/2015 - 01/2014
2	Capsules (Microcapsules)IBA 01/2015 - 01/2011
2	Caspase 1 (ICE Protease)IBA 02/2014 - 12/2010
2	FlagellinIBA 01/2014 - 10/2012
2	Immunotoxins (Immunotoxin)IBA 01/2013 - 08/2003
2	Calmodulin (Calcium-Dependent Activator Protein)IBA 01/2013 - 08/2009
2	von Willebrand FactorIBA 12/2012 - 07/2009
2	LipidsIBA 10/2012 - 02/2003
2	DNA (Deoxyribonucleic Acid)IBA 02/2012 - 05/2003
2	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2008 - 02/2008
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 12/2004 - 10/2004
1	Enzyme Precursors (Zymogens)IBA 12/2022
1	Botulinum Toxins (Botulinum Toxin)IBA 01/2022
1	CarrageenanIBA 01/2022
1	Formaldehyde (Formol)FDA Link 01/2022
1	DNA-Directed RNA Polymerases (RNA Polymerase)IBA 12/2019
1	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 05/2019
1	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 05/2019
1	Therapeutic UsesIBA 05/2019
1	Combined VaccinesIBA 10/2018
1	BiothraxIBA 10/2018
1	Capsid Proteins (Capsid Protein)IBA 10/2018
1	Subunit VaccinesIBA 10/2018
1	NanovaccinesIBA 10/2018
1	Biological Warfare AgentsIBA 10/2018
1	Nimodipine (Modus)FDA LinkGeneric 01/2016
1	leucine receptorIBA 01/2016
1	sulforaphaneIBA 01/2016
1	raxibacumabIBA 12/2015
1	Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA 10/2015
1	Tetanus Toxoid (Vaccine, Tetanus)FDA Link 08/2015
1	15-deoxyprostaglandin J2IBA 03/2015
1	Indicators and Reagents (Reagents)IBA 09/2014
1	MicroRNAs (MicroRNA)IBA 09/2014
1	Cytotoxins (Cytolysins)IBA 09/2014
1	Amino Acids FDA Link 04/2014
1	Bicarbonates (Hydrogen Carbonate)IBA 03/2014

Therapy/Procedure

29	Therapeutics 01/2023 - 02/2002
3	Drug Therapy (Chemotherapy) 08/2003 - 08/2002
1	Analgesia 01/2022
1	Intravenous Administration 10/2019